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Spo13 facilitates monopolin recruitment to kinetochores and regulates maintenance of centromeric cohesion

Alliance of Genome Resources2026-08-01 收录

减数分裂染色体

着丝粒黏连调控

数据链接：

https://www.yeastgenome.org/dataset/GSE4813 数据链接链接失效反馈

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资源简介：

BACKGROUND: Cells undergoing meiosis perform two consecutive divisions after a single round of DNA replication

应用场景：

减数分裂染色体

染色质ChIP-seq分析

Successful meiotic recombination, and thus fertility, depends on conserved axis proteins that organize chromosomes into arrays of anchored chromatin loops and provide a protected environment for DNA e

NIAID Data Ecosystem40

Stage-resolved genome architecture maps throughout meiotic prophase link regional variations in chromosome organization with homolog alignment (Hi-C, Cut&Tag, RNA-seq)

减数分裂染色体

染色体配对

During meiosis, chromosomes undergo extensive changes in structure and intranuclear positioning. How these chromosome organization changes occur and how they influence meiosis-specific chromosome even

NIAID Data Ecosystem30

Principles of chromosome organization for meiotic recombination

减数分裂染色体

染色质免疫沉淀测序

In meiotic cells, chromosomes are organized as chromatin loop arrays anchored to a protein axis. This organization is essential to regulate meiotic recombination, from DNA double-strand break (DSB) fo

NIAID Data Ecosystem20

X-Y pairing efficiency in pachytene spermatocytes.

减数分裂染色体

生殖细胞遗传

aIn a few cells, the Y or the Y*X chromosome appear to be missing. Some of them might have achieved a centromere pairing with the X chromosome or have been lost during cell spreading. bThe average PAR

NIAID Data Ecosystem30

Rec8 guides canonical Spo11 distribution along yeast meiotic chromosomes

减数分裂染色体

DNA双链断裂调控

Spo11-mediated DNA double strand breaks (DSBs) that initiate meiotic recombination are temporally and spatially controlled. The meiotic cohesin Rec8 has been implicated in regulating DSB formation, bu

NIAID Data Ecosystem20

Spo13 facilitates monopolin recruitment to kinetochores and regulates maintenance of centromeric cohesion

资源简介：

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