Structure of CEACAM5 A3-B3 domain in Complex with Tusamitamab Fab

Structure of CEACAM5 A3-B3 domain in Complex with Tusamitamab Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 5, ... Authors: Kumar, A, Bertrand, T, Rapisarda, C, Rak, A. Deposit date: 2022-12-06 Release date: 2024-01-24 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.11 Å) Cite: Structural insights into epitope-paratope interactions of a monoclonal antibody targeting CEACAM5-expressing tumors. Nat Commun, 15, 2024与图塞妥单抗（Tusamitamab）Fab片段结合的CEACAM5 A3-B3结构域复合物结构 复合物组成描述：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、癌胚抗原相关细胞黏附分子5（CEACAM5）…… 作者：Kumar A、Bertrand T、Rapisarda C、Rak A 入库日期：2022-12-06 发布日期：2024-01-24 最后修改日期：2024-11-13 实验方法：电子显微镜（分辨率3.11 Å） 引用文献：《靶向表达CEACAM5肿瘤的单克隆抗体表位-互补位相互作用的结构解析》，《自然·通讯》，第15卷，2024年