Supplemental Material for Wilson and Postlethwait, 2024

Zebrafish sex chromosomes have a region, unique in the genome, that contains protein-coding genes silenced in ovaries but expressed in testes and then transiently expressed in embryos as they begin to express their own genes. This region also contains maternal-specific genes encoding the protein-synthesis machinery used specifically by developing embryos, and is adjacent to mir-430,  which targets maternal transcripts for degradation. This region defines a distinct maternal-to-zygotic-transisition block of genes.