We call these novel candidate genes because they are not listed as being associated with the trait of interest in either the GWAS catalog or dbGaP, and they have top posterior enrichment probabilities
This table describes significant pathway terms over-represented in core regions based on GeneMerge1.2 software. Pop-frec describes the frequency of genes in the population with this pathway, and CR-fr
None of the BRCA1/2 mutations demonstrated significant associations with FMR1. The single mutation noted in 10 patients was in 9 women associated with a het-norm/low FMR1 sub-genotype.
