Samples for CNIC-Proteomics Nextflow pipelines: nf-PTM-Analyzer

We present several input sample files for the execution of various Nextflow pipelines developed by the Cardiovascular Proteomics Lab/Proteomics Unit at the National Centre for Cardiovascular Research (CNIC, https://www.cnic.es). The nf-PTM-Analyzer enhances the identification and quantification of Post-Translational Modifications (PTMs) (https://github.com/CNIC-Proteomics/nf-PTM-compass). The available sample files are as follows: heteroplasmic_heart.zip: Heart tissue. Input files for ReportAnalysis, derived from the study by Bagwan N, Bonzon-Kulichenko E, Calvo E, et al. (*), with results from iSanXoT and PTM-compass analysis. heteroplasmic_liver.zip: Liver tissue. Input files for ReportAnalysis, derived from the before study (*), with results from iSanXoT and PTM-compass analysis. heteroplasmic_muscle.zip: Muscle tissue. Input files for ReportAnalysis, derived from the before study (*), with results from iSanXoT and PTM-compass analysis. (*) Bagwan N, Bonzon-Kulichenko E, Calvo E, et al. Comprehensive Quantification of the Modified Proteome Reveals Oxidative Heart Damage in Mitochondrial Heteroplasmy. Cell Reports. 2018;23(12):3685-3697.e4. doi:10.1016/j.celrep.2018.05.080本数据集提供若干输入样本文件，用于执行西班牙国家心血管研究中心（National Centre for Cardiovascular Research, CNIC，https://www.cnic.es）心血管蛋白质组学实验室/蛋白质组学单元开发的多款Nextflow流程。 nf-PTM-Analyzer可优化翻译后修饰（Post-Translational Modifications, PTMs）的鉴定与定量分析，相关项目地址为https://github.com/CNIC-Proteomics/nf-PTM-compass。 本次提供的可用样本文件如下： heteroplasmic_heart.zip：对应心脏组织样本，为ReportAnalysis流程的输入文件，源自Bagwan N、Bonzon-Kulichenko E、Calvo E等人的研究（*），包含iSanXoT与PTM-compass的分析结果。 heteroplasmic_liver.zip：对应肝脏组织样本，为ReportAnalysis流程的输入文件，源自前述研究（*），包含iSanXoT与PTM-compass的分析结果。 heteroplasmic_muscle.zip：对应肌肉组织样本，为ReportAnalysis流程的输入文件，源自前述研究（*），包含iSanXoT与PTM-compass的分析结果。 （*）Bagwan N, Bonzon-Kulichenko E, Calvo E, 等. 修饰蛋白质组的全面定量揭示线粒体异质性相关心脏氧化损伤. Cell Reports. 2018;23(12):3685-3697.e4. doi:10.1016/j.celrep.2018.05.080