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DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations. DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations

NIAID Data Ecosystem2026-03-12 收录

DNA复制时序

染色体易位机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA679566 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2020-11-19

早衰症

DNA复制时序

Progeroid syndromes are rare genetic disorders that phenotypically resemble natural aging. Despite identification of causal mutations, mechanisms that generate their clinical manifestations remain elu

NIAID Data Ecosystem70

Global early replication disrupts gene expression and chromatin conformation in a single cell cycle: MNAse-Seq mapping

DNA复制时序

染色质景观调控

The early embryonic divisions of many organisms, including fish, flies and frogs are characterised by a very rapid S-phase caused by high rates of replication initiation. In somatic cells, S-phase is

NIAID Data Ecosystem70

Aalysis of replication timing in the RPE1 and HCT116 cell line. Aalysis of replication timing in the RPE1 and HCT116 cell line

DNA复制时序

细胞周期

Mapping replication timing in the RPE1 and HCT116 cell lines revealed differences in replication dynamics and replication domain structures in the two cell lines Overall design: Asynchronously growing

NIAID Data Ecosystem50

Arabidopsis thaliana Chromosome 4 Replicates in Two Phases That Correlate with Chromatin State

DNA复制时序

染色质表观遗传调控

DNA replication programs have been studied extensively in yeast and animal systems, where they have been shown to correlate with gene expression and certain epigenetic modifications. Despite the conse

NIAID Data Ecosystem70

Functional Centromeres Determine the Activation Time of Pericentric Origins of DNA Replication in Saccharomyces cerevisiae

着丝粒功能

DNA复制时序

The centromeric regions of all Saccharomyces cerevisiae chromosomes are found in early replicating domains, a property conserved among centromeres in fungi and some higher eukaryotes. Surprisingly, li

NIAID Data Ecosystem60

DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations. DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations

资源简介：

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