five

Early induction of neurogenic program by Ascl1ERT2 and Neurog2ERT2

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE174238
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Spinal cord-derived astrocytes underwent direct neuronal reprogramming following the activation of Ascl1ERT2 and Neurog2ERT2 for 24 hours Spinal cord-derived astrocytes were transduced in cultures with retrovirus enconding a tamoxifen-dependent form of Ascl1 and Neurog2.Cells were treated for 24 hours, then transduced cells were FACS-sorted and their transcriptome analyzed.
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2021-08-11
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