The PODER cross-ancestry long-read RNA-seq dataset

Table legends: column_descriptions.docx: Extended description of columns in selected tables. 00_sample_metadata: Sample and experimental metadata pertaining to each LR-RNA-seq sample. 01_uma_gtf: Unfiltered merged annotation (UMA) GTF for all spliced intron chains discovered by each of the tools. 02_uma_mt: Metadata table for SQANTI QC, Recount3 support, protein prediction, and other relevant characteristics for each transcript in the UMA annotation used to filter transcripts. 03_poder_gtf: Final PODER GTF, including predicted CDSs for novel transcripts and annotated CDSs for known transcripts. 04_poder_mt: Metadata table for SQANTI QC, Recount3 support, protein prediction, and other relevant characteristics for each transcript in PODER. 06_poder_t_counts: PODER transcript counts in each sample as quantified by lr-kallisto. 07_poder_g_counts: PODER gene counts in each sample as quantified by lr-kallisto. 08_mage_t_counts_poder: Transcript counts for the MAGE RNA-seq dataset computed using the PODER annotation with kallisto. 09_mage_t_counts_gencode: Transcript counts for the MAGE RNA-seq dataset computed using the GENCODE annotation with kallisto. 10_mage_t_counts_enh: Transcript counts for the MAGE RNA-seq dataset computed using the Enhanced GENCODE annotation with kallisto. 11_astu: Allele-specific transcript usage results. 12_ase: Allele-specific expression results. 13_mage_tau: Tau values for Enhanced GENCODE transcripts computed on the MAGE RNA-seq dataset. 14_gwas_enrichments: GWAS enrichment results for ASTU genes overlapping GWAS genes. 16_inter_catalog_overlap: Boolean detection of transcripts across PODER, annotations (GENCODE, RefSeq) and other RNA-seq / LR-RNA-seq-derived transcript catalogs (CHESS, GTEx, ENCODE4). 17_personalized_hg38: Isoforms and their intron chains detected using personalized-GRCh38s. 18_enh_gencode: Enhanced GENCODE GTF with novel transcripts from PODER added to all annotated transcripts from GENCODE v47表格标注说明： column_descriptions.docx：针对所选表格各列的详细说明文档 00_sample_metadata：对应各长读长RNA测序（LR-RNA-seq）样本的样本与实验元数据 01_uma_gtf：包含各工具所发现的全部剪接内含子链的未过滤合并注释（Unfiltered Merged Annotation, UMA）GTF（Gene Transfer Format）文件 02_uma_mt：用于UMA注释中转录本筛选的元数据表，涵盖各转录本的SQANTI质量控制（Quality Control, QC）结果、Recount3支持度、蛋白质预测特征及其他相关属性 03_poder_gtf：最终版PODER GTF文件，包含新转录本的预测编码序列（Coding Sequence, CDS）及已知转录本的注释编码序列（CDS） 04_poder_mt：针对PODER注释中各转录本的SQANTI质量控制、Recount3支持度、蛋白质预测特征及其他相关属性的元数据表 06_poder_t_counts：通过lr-kallisto定量得到的各样本中PODER注释的转录本计数数据 07_poder_g_counts：通过lr-kallisto定量得到的各样本中PODER注释的基因计数数据 08_mage_t_counts_poder：采用PODER注释结合kallisto定量得到的MAGE RNA-seq数据集的转录本计数数据 09_mage_t_counts_gencode：采用GENCODE注释结合kallisto定量得到的MAGE RNA-seq数据集的转录本计数数据 10_mage_t_counts_enh：采用增强版GENCODE注释结合kallisto定量得到的MAGE RNA-seq数据集的转录本计数数据 11_astu：等位基因特异性转录本使用（Allele-Specific Transcript Usage, ASTU）分析结果 12_ase：等位基因特异性表达（Allele-Specific Expression, ASE）分析结果 13_mage_tau：基于MAGE RNA-seq数据集计算得到的增强版GENCODE转录本的Tau指数值 14_gwas_enrichments：针对与全基因组关联研究（Genome-Wide Association Study, GWAS）基因存在重叠的ASTU基因的GWAS富集分析结果 16_inter_catalog_overlap：跨PODER、各类注释（GENCODE、参考序列（Reference Sequence, RefSeq））及其他RNA-seq/长读长RNA测序（LR-RNA-seq）来源的转录本目录（CHESS、GTEx、ENCODE4）的转录本布尔型检测结果 17_personalized_hg38：基于个性化GRCh38基因组检测得到的转录本亚型及其内含子链信息 18_enh_gencode：增强版GENCODE GTF文件，将PODER来源的新转录本添加至GENCODE v47的全部已注释转录本中