Dataset: Long term fMRI adaptation depends on adapter response in face-selective cortex

Repetition suppression (RS) reflects a neural attenuation during repeated stimulation. We used fMRI and the subsequent memory paradigm to test the predictive coding hypothesis for RS during visual memory processing by investigating the interaction between RS and differences due to memory in category-selective cortex (FFA, pSTS, PPA, and RSC). Fifty-six participants encoded face and house stimuli twice, followed by an immediate and delayed (48 h) recognition memory assessment. Linear Mixed Model analyses with repetition, subsequent recognition performance, and their interaction as fixed effects revealed that absolute RS during encoding interacts with probability of future remembrance in face-selective cortex. This effect was not observed for relative RS, i.e. when controlled for adapter-response. The findings also reveal an association between adapter response and RS, both for short and long term (48h) intervals, after controlling for the mathematical dependence between both measures. Th...

重复抑制（Repetition Suppression，RS）指重复刺激过程中发生的神经活动衰减现象。本研究采用功能磁共振成像（functional Magnetic Resonance Imaging，fMRI）结合后续记忆范式，通过探究类别选择性皮层内的梭状回面孔区（Fusiform Face Area，FFA）、后颞上沟（posterior Superior Temporal Sulcus，pSTS）、海马旁回位置区（Parahippocampal Place Area，PPA）以及压后皮层（Retrosplenial Cortex，RSC）的重复抑制与记忆相关差异之间的交互作用，检验视觉记忆加工过程中重复抑制的预测编码假说。
56名参与者先后两次编码面孔与房屋刺激材料，随后分别开展即时及延迟（48小时）再认记忆测评。以重复次数、后续再认表现及其交互作用作为固定效应的线性混合模型（Linear Mixed Model）分析结果显示，面孔选择性皮层内的绝对重复抑制在编码阶段与未来记忆留存概率存在交互效应；而在通过适配器反应进行控制后得到的相对重复抑制中，则未观测到该效应。
本研究同时发现，在控制两种测量指标间的数学依赖性后，适配器反应与重复抑制之间存在关联，且该关联在短时及长时（48小时）间隔下均成立。