Raw data from transcriptome sequencing of 12 colorectal cancer patients in Ruijin hospital (performed by Dr. Jing Sun))

The study was approved by the Ethical Committee of Ruijin Hospital with a clinical trial registration number NCT04714814. Among the prospective patient cohort collected, 12 CRC individuals for the High-throughput transcriptome analysis were strictly screened in our center, without any medical treatment before recruitment. Total RNA was isolated from the surgically discarded normal and tumor colorectal tissues of these 12 CRC individuals. Then, the cDNA library was constructed, and high-throughput sequencing was performed at Shanghai Jiao Tong University School of Medicine (Shanghai, China) using the HiSeq 4000 (Illumina, San Diego, CA). Raw data of the gene expression and clinical information about them is listed below.

本研究经瑞金医院伦理委员会批准，临床试验注册号为NCT04714814。在本次收集的前瞻性患者队列中，本中心严格筛选出12名结直肠癌（Colorectal Cancer, CRC）患者用于高通量转录组分析（High-throughput transcriptome analysis），所有受试者入组前均未接受过任何临床治疗。从这12名CRC患者手术切除后废弃的结直肠正常组织与肿瘤组织中提取总RNA。随后构建cDNA文库，并于中国上海交通大学医学院使用HiSeq 4000测序仪（Illumina，美国加利福尼亚州圣地亚哥）完成高通量测序。相关基因表达原始数据及患者临床信息详见下文。