Loss of BAF (mSWI/SNF) complexes causes global transcriptional and chromatin state changes in forebrain development
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https://www.ncbi.nlm.nih.gov/sra/SRP064617
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资源简介:
We report the genome-wide increase in H3K27 trimethylation (H3K27me3) in murine embryonic cortices as a result of conditional double knock-out (dcKO) of BAF155/BAF170 complex. Overall design: 1) Comparison of H3K27me3 levels in murine cortical tissues from embryonic day 13.5 (E13.5) in Emx1-Cre BAF155/BAF170 dcKO and controls. 2) Comparison of H3K27me3 levels in murine cortical tissues from postnatal day 1 (P1) in Nex-Cre BAF155/BAF170 dcKO and controls.
创建时间:
2017-09-17



