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Whole genome DNA methylation analysis of human CD8 T cell specific for the Yellow fever virus vaccine

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=49873cade0d9c6ec8246b6cb11c74149
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资源简介:
Central questions regarding the origin of memory CD8 T cells, their turnover and longevity in vivo are not well-defined in humans. Here, we have used the highly efficacious live yellow fever virus vaccine (YFV-17D) to address these issues in the context of a primary acute viral infection. We interrogated genome-wide CpG methylation of YFV tetramer-specific CD8 T cells. These findings provide a better understanding of how memory CD8 T cells are formed and maintained in humans.
提供机构:
Emory University
创建时间:
2022-02-20
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