Replication Data for "The Effects of Green Tea and/or Licorice Aqueous Extracts on Hepatic Oxidant/Antioxidant System of Dimethylnitrosamine-Intoxicated Male Albino Rats."

Description of data 1. Effects of the tested materials on hepatic content of total thiols Table 6 demonstrated that the general effect, in between groups, was found by one way ANOVA to be very highly significant (P < 0.001). The combination of green tea and licorice increased the hepatic content of total thiols by 18.03 % when it was compared with normal control, while green tea or licorice had no significant change. DMN decreased significantly that content by 22.40 %, while green tea, licorice or the combination of both antagonized the bad effect of DMN by increasing that content significantly by 38.73 %, 13.38 % and 33.10 % respectively as shown in table 1. 2. Effects of the tested materials on hepatic content of reduced glutathione (GSH) Table (6) revealed that the general effect, in between groups, was found by one way ANOVA to be very highly significant (P < 0.001). Licorice or green tea increased significantly the hepatic content of GSH in relation to normal control by 56.60 % or 35.85 % respectively, while the mixture decreased that level significantly by 20.75 %. On the other hand, DMN caused a profound increase in hepatic content of GSH relative to normal control by 64.15 %. Licorice or green tea extract administration to DMN-injected animals increased that content by 72.41 % or 22.99 % respectively while the mixture decreased that content insignificantly as shown in table 1. 3. Effects of the tested materials on hepatic activity of glutathione reductase (GSHr) Table 6 depicted that the general effect, in between groups, was found by one way ANOVA to be very highly significant (P < 0.001). Licorice, green tea or the combination decreased significantly the hepatic activity of glutathione reductase in relation to normal control by 25.60 %, 13.60 % or 14.40 % respectively, while DMN significantly increased the activity by 12.00 %. Green tea, licorice, or the mixture antagonized the stimulating effect of DMN by decreasing that activity by 30.71 %, 20.00 % or 34.29 % respectively as revealed in table 2. 4. Effect of the tested materials on hepatic of total glutathione-S-transferase (GST) activity Table 6 revealed that the general effect, in between groups, was found by one way ANOVA to be very highly significant (P < 0.001). Green tea, licorice or the mixture caused significant decreases in the hepatic activity of GST relative to normal control by 10.79 %, 26.75 % or 14.24 % respectively, while DMN exerted a significant increase in that activity by 17.37 %. Green tea, licorice or the mixture exerted significant decrease of the elevated hepatic GST activity of DMN-administered animals by 35.85 %, 9.65 % or 31.07 % respectively as shown in table 2. 5. Effect of the tested materials on hepatic of total glutathione peroxidase (GSHpx) activity Table 6 revealed that the general effect, in between groups, was found by one way ANOVA to be very highly significant (P < 0.001). Green tea exerted an insignificant change in the GSHpx activity, while licorice or the mixture produced significant decreases by 25.52 % or 12.74 % respectively when compared with normal control. On the other hand, DMN caused a significant increase by 11.79 % relative to normal control. Green tea, licorice or the mixture administration to DMN-injected animals caused significant decreases in that activity by 30.38 %, 12.66 % or 27.43 % respectively as shown in table 2. 6. Effects of the tested materials on hepatic of total superoxide dismutase (SOD) activity Table 7 revealed that the general effect, in between groups, was found by one way ANOVA to be very highly significant (P < 0.001). Green tea or licorice decreased significantly the hepatic activity of SOD in relation to normal control by 86.56 % or 62.26 % respectively, while the combination increased significantly that activity by 19.20 %. DMN decreased significantly that activity by 17 %. Green tea or the combination did not affect the lowering effect of DMN, but enhances insignificantly the SOD activity. On the other hand, licorice profound the lowering effect of DMN by decreasing that activity by 15.37 % as represented in table 3. 7. Effects of the tested materials on hepatic activity of catalase Table 7 revealed that the general effect, in between groups, was found by one way ANOVA to be very highly significant (P < 0.001). Green tea, licorice or the combination decreased the hepatic activity of catalase by 27.70 %, 10.14 or 30.41 % respectively, while DMN increased significantly that activity by 28.38 % relative to normal control. Green tea, licorice or the mixture attenuated the stimulating effect of DMN by decreasing the catalase activity by 48.79 %, 20.53 % or 8.42 % respectively relative to DMN-injected control rats as shown in table 3. 8. Effects of the tested materials on hepatic content vitamin C Table 7 revealed that the general effect, in between groups, was found by one way ANOVA to be very highly significant (P < 0.01). All the treated compounds either the sole...