nCounter analysis of patients progressed to TKIs
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235432
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资源简介：
A prevalence study was conducted for MET amplification and overexpression in liquid biopsy samples from patients with NSCLC who relapsed on ALK, ROS1 or RET tyrosine kinase inhibitors. MET-mediated resistance was detected in 37.5% of tissue biopsies, which allow the detection of MET overexpression, compared to 7.4% of liquid biopsies. This study highlights the importance of considering MET overexpression as a resistance driver to fusion targeted therapies 28 liquid biopsy samples from non-small cell lung cancer patients (NSCLC) with ALK, ROS1 and RET fusions in progression to ALK TKIs (crizotinib, alectinib, lorlatinib, ceritinib) were analyzed by nCounter
创建时间：
2023-06-25
