Loss of Regnase-1 promotes resilience to Klebsiella pneumoniae
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
Excessive inflammatory response can cause collateral tissue damage. Regnase-1 (zc4h12a) is an RNA binding protein that degrades pro-inflammatory transcripts. The role of Regnase-1 in bacterial immunity is poorly defined. Mice deficient in Regnase-1 are more resistant to Klebsiella pneumoniae and this correlates with enrichment of Type-I IFN-related genes in the lungs.
创建时间：
2022-02-01
