Modular microenvironment components reproduce vascular dynamics de novo in a multi-scale agent-based model: VASCULAR FUNCTION

Data and results for `VASCULAR FUNCTION` simulations.

Simulations of cancerous cells in colony and tissue contexts with pattern and various graph layouts with degradation by cancerous cells and vascular remodeling. Each condition is run for 15 days (21600 ticks) with 10 replicates (random seeds 0 - 9).
Cancerous cells (max_height x 1.5, meta_pref x 1.5, migra_threshold x 0.5) are introduced to the center of the environment after a 1 day delay. Snapshots are taken every 0.5 days (720 ticks). The data folder contains .tar.xz compressed replicate sets.
The data.graph folder contains .tar.xz compressed replicate sets for .GRAPH output. The results folder contains .pkl files of data parsed into arrays. Simulations are labeled as: [context]_[sites]_[layout]

- [context]
- C = colony context, cancerous cells only
- CH = tissue context, cancerous cells and healthy cells
- [sites]
- PATTERN = site architecture defined by pattern
- GRAPH = site architecture defined by graph layout
- [layout]
- simulations with PATTERN do not have a layout label
- Lav = line root graph with one artery and one vein (L11)
- Lava = line root graph with two arteries and one vein (L21)
- Lvav = line root graph with one artery and two veins (L12)
- Sav = single root graph with one artery and one vein (S11)
- Savav = single root graph with two arteries and two veins (S22)

本数据集包含血管功能（VASCULAR FUNCTION）模拟相关的数据与结果。该模拟针对集落与组织环境中的癌细胞展开，结合预设模式与多种图布局，模拟癌细胞降解与血管重塑过程。每个实验条件均运行15天（对应21600个时间步长），并设置10次重复实验（随机种子取值为0至9）。
经过1天的延迟后，将参数调整为max_height ×1.5、meta_pref ×1.5、migra_threshold ×0.5的癌细胞接种至实验环境的中心区域。每0.5天（720个时间步长）采集一次系统快照。数据文件夹内包含经.tar.xz压缩的重复实验数据集。
data.graph文件夹内包含.GRAPH格式输出结果的.tar.xz压缩重复实验数据集。results文件夹内包含已解析为数组格式的.pkl格式数据文件。模拟实验的命名规则为：[实验环境]_[位点结构]_[图布局]。
- [实验环境]
- C：集落环境，仅包含癌细胞
- CH：组织环境，包含癌细胞与健康细胞
- [位点结构]
- PATTERN：由预设模式定义的位点架构
- GRAPH：由图布局定义的位点架构
- [图布局]
- 采用PATTERN模式的实验无布局标签
- Lav：单动脉单静脉的线状根图（L11）
- Lava：双动脉单静脉的线状根图（L21）
- Lvav：单动脉双静脉的线状根图（L12）
- Sav：单动脉单静脉的单根图（S11）
- Savav：双动脉双静脉的单根图（S22）