Allelic effects and transmission of QTLs mapped in the DABC population.

QTLs are indicated with chromosome: location in Mb, *indicates QTLs that are shared between DABC and PVGBC populations. The p-values from effect plots in DABC are given, analyzed by Student's t-test, p-values ≤0.05 were considered significant. a Onset and incidence gave similar results and ONS is shown as a representative for susceptibility phenotypes. b Maximum and cumulative EAE scores and duration of EAE showed similar results and MAX represents the severity phenotypes. Bold indicates significant p-values for QTLs showing evidence for parent-of-origin dependence. Abbreviations: ONS  =  onset of EAE, MAX  =  maximum EAE score, WL  =  weight loss, Allele  =  disease predisposing allele, D  =  DA, P  =  PVG, Trans  =  transmission of disease-predisposing allele, Cross  =  indicates reciprocal cross in which QTL was identified, Mat  =  maternal transmission, Pat  =  paternal transmission and Mito  =  mitochondria.