Allelic effects and transmission of QTLs mapped in the DABC population.

QTLs are indicated with chromosome: location in Mb, *indicates QTLs that are shared between DABC and PVGBC populations. The p-values from effect plots in DABC are given, analyzed by Student's t-test, p-values ≤0.05 were considered significant. a Onset and incidence gave similar results and ONS is shown as a representative for susceptibility phenotypes. b Maximum and cumulative EAE scores and duration of EAE showed similar results and MAX represents the severity phenotypes. Bold indicates significant p-values for QTLs showing evidence for parent-of-origin dependence. Abbreviations: ONS = onset of EAE, MAX = maximum EAE score, WL = weight loss, Allele = disease predisposing allele, D = DA, P = PVG, Trans = transmission of disease-predisposing allele, Cross = indicates reciprocal cross in which QTL was identified, Mat = maternal transmission, Pat = paternal transmission and Mito = mitochondria.