Bmp7

ENCODES a protein that exhibits heparin binding; BMP receptor binding (ortholog); growth factor activity (ortholog); INVOLVED IN regulation of phosphorylation; response to estradiol; response to peptide hormone; PARTICIPATES IN Bone morphogenetic proteins signaling pathway; Hedgehog signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; ASSOCIATED WITH acute kidney tubular necrosis; Diabetic Nephropathies; Femoral Fractures; FOUND IN collagen-containing extracellular matrix; extracellular space; vesicle; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-Tetrachlorodibenzofuran

编码一种具有肝素结合能力的蛋白质；BMP受体结合（同源）；生长因子活性（同源）；参与调控磷酸化过程；对雌二醇的反应；对肽类激素的反应；参与骨形态发生蛋白信号通路； hedgehog 信号通路；转化生长因子-β超家族介导的信号通路；与急性肾小管坏死、糖尿病肾病、股骨骨折等相关；存在于含有胶原蛋白的细胞外基质、细胞外空间、囊泡中；与17β-雌二醇、17β-雌二醇3-苯甲酸酯、2,3,7,8-四氯二苯并呋喃相互作用。