Independent and joint effects of coffee drinking and GRIN2A-rs4998386 for Parkinson disease.

aOdds ratios (OR) and 95% confidence intervals (CI) computed using unconditional logistic regression and adjusted for sex, age in quartiles, ever cigarette smoking, and dataset (1974 cases, 2494 controls).bOdds ratios (OR) and 95% confidence intervals (CI) computed using conditional logistic regression and adjusted for sex, age in quartiles, and ever cigarette smoking (315 cases, 315 controls).cOdds ratios (OR) and 95% confidence intervals (CI) computed by pooling individual data from the matched and unmatched case-control analyses and adjusted for sex, age in quartiles, ever cigarette smoking, and dataset (2289 cases, 2809 controls).dGlobal test of interaction: p-values were computed using a likelihood ratio test that compared the likelihood of models with and without interaction terms.Independent and joint effects of coffee drinking and GRIN2A-rs4998386 for Parkinson disease.