Conformation of the budding yeast pericentromere in metaphase. Conformation of the budding yeast pericentromere in metaphase

High-resolution Hi-C in metaphase in wild type cells with and without tension, chl4Δ with tension, and sgo1-3A and sgo1Δ without tension Overall design: Purpose: To determine how pericentromeric chromosome conformation changes in response to spindle tension and to the absence of pericentromeric cohesin and condensin.