Cancer Moonshot Biobank - Lung Cancer Collection (CMB-LCA)

The Cancer Moonshot Biobank is a National Cancer Institute initiative to support current and future investigations into drug resistance and sensitivity and other NCI-sponsored cancer research initiatives, with an aim of improving researchers' understanding of cancer and how to intervene in cancer initiation and progression. During the course of this study, biospecimens (blood and tissue removed during medical procedures) and associated data will be collected longitudinally from at least 1000 patients across at least 10 cancer types, who represent the demographic diversity of the U.S. and receiving standard of care cancer treatment at multiple NCI Community Oncology Research Program (NCORP) sites. This collection contains de-identified radiology and histopathology imaging procured from subjects in NCI’s Cancer Moonshot Biobank-Lung Cancer (CMB-LCA) cohort. Associated genomic, phenotypic and clinical data will be hosted by The Database of Genotypes and Phenotypes (dbGaP) and other NCI databases.癌症登月计划生物样本库（Cancer Moonshot Biobank）是美国国家癌症研究所（National Cancer Institute, NCI）发起的一项研究倡议，旨在支持当前及未来针对药物耐药性、敏感性以及其他由NCI资助的癌症研究项目，以期加深研究者对癌症的认知，并探索干预癌症发生与进展的有效手段。本研究将纵向收集至少10种癌症类型、至少1000名患者的生物样本（即医疗操作中获取的血液与组织）及相关数据；这些患者覆盖美国人口的统计学多样性特征，且均在多个NCI社区肿瘤研究计划（NCI Community Oncology Research Program, NCORP）站点接受标准癌症治疗。 本数据集包含从NCI癌症登月计划生物样本库-肺癌队列（CMB-LCA）受试者中获取的去标识化放射学影像与组织病理学成像数据。相关的基因组、表型及临床数据将由基因型与表型数据库（Database of Genotypes and Phenotypes, dbGaP）及其他NCI数据库进行托管。

搜集汇总

背景与挑战

背景概述

该数据集是Cancer Moonshot Biobank项目的肺癌子集，专注于收集去标识化的放射学和病理学影像数据，来自至少1000名代表美国人口多样性的患者，并与其他基因组和临床数据关联，以支持癌症药物耐药性和敏感性研究。