scRNA-seq of CXCR4(+/-) CD25-CAR-T treatment in AML PDX

de-identified scRNA-seq datasets (h5Seurat format) of CAR-T cells and AML blasts derived from PDX mice. combined.carT.h5seurat: CD25-targeting CAR-T cells from PDX bone marrow at 4 weeks and 5 months merge_Liver_Spleen.h5seurat: AML-blasts and CD25-targeting CAR-T cells from PDX spleen and liver at 2.5 weeks本数据集为采用h5Seurat格式的去标识化单细胞RNA测序（single-cell RNA sequencing, scRNA-seq）数据集，包含源自患者来源的异种移植（Patient-Derived Xenografts, PDX）小鼠的嵌合抗原受体T细胞（Chimeric Antigen Receptor T Cells, CAR-T）与急性髓系白血病母细胞（AML blasts）。 combined.carT.h5seurat：来自PDX小鼠骨髓的CD25靶向CAR-T细胞，采集时间为4周与5个月； merge_Liver_Spleen.h5seurat：来自PDX小鼠脾脏与肝脏的AML母细胞与CD25靶向CAR-T细胞，采集时间为2.5周。