Krüppel-like factor 4 regulates the cytolytic effector function of exhausted CD8 T-cells [RNA-Seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE212804
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To identify the role of KLF4 on exhausted CD8 T-cells, we retrovirally transduced Klf4 into OT-I CD8 T-cells on day1 of in vitro exhaustion model and repeatedly treated OVA peptide to induce exhaustion. Then we analyzed the gene expression profiles of these transduced cells by RNA-sequencing. Comparative gene expression profiling analysis of RNA-seq data for CD8 T-cells transduced with MigRI and Klf4
创建时间:
2023-01-04



