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Impact of the mineralocorticoid receptor on differential gene expression in endothelial cells

NIAID Data Ecosystem2026-05-26 收录

内皮细胞转录组

盐皮质激素受体信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP165263 数据链接链接失效反馈

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资源简介：

Comparative transcriptome analysis by RNAseq of human umbilical vein endothelial cells (HUVECs) after aldosterone (100nM) stimulation and siRNA knockdown of the mineralocorticoid receptor versus respective controls.

应用场景：

创建时间：

2018-10-13

内皮细胞转录组

基因功能沉默分析

RNA sequencing for HUVECs treated with si-control or si-FLRT2 Overall design: mRNA profiles of HUVECs. Four experiments for each group (si-cont and si-FLRT2).

NIAID Data Ecosystem70

Bulk RNA sequecning of control and Dimethyloxalylglycine (DMOG) treated Human Primary Pulmonary artery endothelial cells (ATCC: PCS-100-022). Bulk RNA sequecning of control and Dimethyloxalylglycine (DMOG) treated Human Primary Pulmonary artery endothelial cells (ATCC: PCS-100-022)

内皮细胞转录组

血管生成调控

We assessed the role of prolyl hydroxylase inhibiton using DMOG on angiogenic competance and metabolic reprogramming of endothelial cells. Overall design: Examination of DMOG treated vs untreated endo

NIAID Data Ecosystem30

Endothelial RNF20 regulates the self-renewal and differentiation of neural precursor cells during embryonic development. Endothelial RNF20 regulates the self-renewal and differentiation of neural precursor cells during embryonic development

胚胎神经发育

内皮细胞转录组

Purpose: To further explore how endothelial RNF20 regulates embryonic neurogenesis, RNA isolated from the endothelial cells of RNF20fl/fl and RNF20cKO-Tie2 brain cortex at E13 was analyzed by RNA-seq

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Expression profiling of lung endothelial cells during metastatic progression. [RNA-Seq]

肿瘤转移

内皮细胞转录组

Lung EC were isolated at sequential stages of tumor progression and bulk RNA-seq analysis was performed. Overall design: Total RNA-sequencing FACS-sorted lung endothelial cells was undertaken. Four in

NIAID Data Ecosystem40

Bulk RNA-seq analysis in pulmonary endothelial cells between saline and LPS group, WT (Fgfr1loxp/loxp) and endothelial Fgfr1-conditional knock out mice (Fgfr1i?EC/i?EC mice).

肺损伤机制

内皮细胞转录组

Endothelial cells (ECs) serve as a semipermeable barrier and play a key role in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). It is well known that fibroblast growth factor recep

NIAID Data Ecosystem30

Impact of the mineralocorticoid receptor on differential gene expression in endothelial cells

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