ApoE4 prime editing
收藏NIAID Data Ecosystem2026-05-10 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP653655
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资源简介：
The alolipoprotein E4 (ApoE4) allele is one of the strongest genetic risk factors for Alzheimer's disease. ApoE4 modification represents a therapeutic strategy to mitigate disease progression. In this study, we applied the prime editor 7 (PE7) system to enable precise and efficient conversion of the ApoE4 allele to the neuroprotective ApoE3 variant.
创建时间：
2025-12-11
