cAb_Rep is a public database that contains 293 B cell repertoires from 108 human healthy, vaccinated, and autoimmune disease donors. The database includes a total of ~4.2 and 1.2 million curated full
Sanger sequencing of BCR IGVH regions in wild type (WT) and TCL1 transgenic mice with intact (TCL1 Nfat2+/+) and deleted (TCL1 Nfat2-/-) NFAT2 expression
RNAi profiling of mouse loss of function mutant using in vivo screening identifies regulators of actin dynamics as key determinants of lymphoma progression
ARID1A, a subunit of the canonical BAF nucleosome remodeling complex, is commonly mutated in lymphomas. Our study shows that ARID1A orchestrates B-cell fate during the germinal center (GC) response, f
CLL stereotyped B-cell receptor immunoglobulin sequences are recurrent in the B-cell repertoire of healthy individuals: apparent lack of central and early peripheral tolerance censoring