Crystal structure of M. tuberculosis C171Q KasA in complex with TLM6
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Crystal structure of M. tuberculosis C171Q KasA in complex with TLM6 Descriptor: (2R)-2-(hexadecanoyloxy)-3-{[(10R)-10-methyloctadecanoyl]oxy}propyl phosphate, (5R)-5-methyl-5-[(1E)-2-methylbuta-1,3-dienyl]-4-oxidanyl-3-[2,2,2-tris(fluoranyl)ethanoyl]thiophen-2-one, 1,2-ETHANEDIOL, ... Authors: Schiebel, J, Kapilashrami, K, Fekete, A, Bommineni, G.R, Schaefer, C.M, Mueller, M.J, Tonge, P.J, Kisker, C. Deposit date: 2013-09-19 Release date: 2013-10-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Basis for the Recognition of Mycolic Acid Precursors by Kasa, a Condensing Enzyme and Drug Target from Mycobacterium Tuberculosis J.Biol.Chem., 288, 2013
结核分枝杆菌(Mycobacterium tuberculosis)C171Q突变KasA与TLM6复合物的晶体结构 配体描述:(2R)-2-(十六酰氧基)-3-{(10R)-10-甲基十八酰氧基}丙基磷酸酯、(5R)-5-甲基-5-[(1E)-2-甲基丁-1,3-二烯基]-4-羟基-3-[2,2,2-三氟乙酰基]噻吩-2-酮、1,2-乙二醇等
作者:Schiebel J、Kapilashrami K、Fekete A、Bommineni G.R、Schaefer C.M、Mueller M.J、Tonge P.J、Kisker C
入库日期:2013-09-19
发布日期:2013-10-09
最后修改日期:2023-12-20
实验方法:X射线衍射(分辨率1.8埃)
引用文献:《结核分枝杆菌来源的缩合酶与药物靶点KasA识别分枝菌酸前体的结构基础》,《Journal of Biological Chemistry》,第288卷,2013年
创建时间:
2013-09-19



