Designed HIV-1 TAR Binding Ligand Descriptor: N-[2-(3-AMINOPROPOXY)-5-(1H-INDOL-5-YL)BENZYL]-N-(2-PIPERAZIN-1-YLETHYL)AMINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*U

Protein Data Bank Japan2024-05-15 更新60

Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox. Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox

RNA靶向

异构体调控

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20

An RNA-based platform to neutralize DNMT1 function AptaDiR is an innovative RNA-based platform to neutralize DNMT1 function

RNA靶向

表观遗传药物开发

DNA methylation is a fundamental epigenetic modification regulating gene expression. Aberrant DNA methylation is the most common molecular lesion in cancer cells. However, medical intervention has bee

NIAID Data Ecosystem70

Intrinsic RNA targeting constrains the utility of CRISPR-Cas13 systems [Screen]

CRISPR-Cas系统

RNA靶向

CRISPR-Cas13 systems have been adapted as versatile toolkits for RNA-related applications. Here we systematically evaluate the performance of several prominent Cas13 family effectors (Cas13a, Cas13b a

NIAID Data Ecosystem20

Programmable RNA-Targeting using CasRx in Flies

资源简介：

相关数据集