Summary of top patterns identified for the glioblastoma dataset assuming no errors.

: estimated coverage; : estimated impurity; ME statistic: Vuong statistic comparing the likelihood under the mutual exclusivity model to the likelihood under the independence model; ME p-value: p-value in the ME test (Vuong's test with ME statistic; adjusted using the Benjamini and Hochberg method). Weight: a mutual exclusivity score, applied in previous studies, which increases with coverage and decreases with impurity; Perm. p-value: adjusted p-value in a weight-based column permutation test. Imbalance: contribution of the most frequently mutated gene in the pattern to the coverage.