Assessment of Airway Resistance and Specic Airway Conductance in Centrally Obese Adults
收藏NIAID Data Ecosystem2026-05-02 收录
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https://zenodo.org/record/11422309
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Background:Obesity's systemic consequences impact pulmonary function, with central obesity exerting a more signicant inuence on pulmonary mechanics than peripheral obesity. Waist circumference (WC) emerges as a crucial parameter, yet research focusing on its specic impact on airway mechanics is limited. Objectives:The study aims to assess whether centrally obese adults exhibit distinct airway resistance and specic airway conductance compared to gender and age-matched controls using cross-sectional study. Methods:Atotal of ninety individuals between the ages of 20 and 40 took part in the study. The research group consisted of forty-ve individuals who were selected based on their waist circumference (WC) being equal to or more than 90 cm in males and 80 cm in women. The remaining 45 individuals were allocated to the control group according to their waist circumference(WC)beingbelow90cminmenand80cminfemales.Abody plethysmograph was used to assess airway resistance and conductance. The statistical methodology employed was appropriate, utilizing the Independent Student's t-test to compare the groups. Results:The ndings showed that the group that participated in the research had a higher airway resistance (P= 0.03) than the control group. No signicant disparity in specic airway conductance was observed between the two groups, following the application of suitable statistical tests for mean comparison (P= 0.99). Conclusion:Centrally obese adults experience increased airway resistance attributable to diminished lung volumes rather than intrinsic airway obstruction. This heightened respiratory effort underscores the importance of maintaining a normal waist circumference to mitigate potential respiratory challenges associated with central obesity
创建时间:
2024-06-02



