This study is aimed to investigate whether adipose tissue Fas signaling exacerbates IBD progression under obese conditions and explored associated mechanisms involving gut microbiota.
Objective: The objective was to study the role of microbiome in the pathogenesis of experimental murine colitis. Methods: We generated bactericidal permeability increasing protein knockout mice, abbre
The imbalance of Th17 and Treg cells was reported to be correlated with the dysbiosis of the gut microbiome. We thus analyzed the composition of the gut microbiota in a steady state and DSS-treated co
