Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 17: N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 17: N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine Descriptor: Histone-lysine N-methyltransferase EHMT2, N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine, S-ADENOSYLMETHIONINE, ... Authors: Babault, N, Xiong, Y, Liu, J, Jin, J. Deposit date: 2017-05-11 Release date: 2017-07-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure-activity relationship studies of G9a-like protein (GLP) inhibitors. Bioorg. Med. Chem., 25, 2017
人源G9a SET结构域（EHMT2）与抑制剂17：N²-环戊基-6,7-二甲氧基-N²-甲基-N⁴-(1-甲基哌啶-4-基)喹唑啉-2,4-二胺的复合物结构
描述项：组蛋白赖氨酸N-甲基转移酶EHMT2、N²-环戊基-6,7-二甲氧基-N²-甲基-N⁴-(1-甲基哌啶-4-基)喹唑啉-2,4-二胺、S-腺苷甲硫氨酸（S-ADENOSYLMETHIONINE）……
作者：Babault, N、Xiong, Y、Liu, J、Jin, J.
存档日期：2017-05-11
发布日期：2017-07-19
最后修改日期：2023-10-04
实验方法：X射线衍射（分辨率1.6 Å）
引用文献：G9a样蛋白（G9a-like protein, GLP）抑制剂的构效关系研究。Bioorg. Med. Chem., 25, 2017
创建时间：
2017-05-11
