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Optimized in vivo base editing restores auditory function in a DFNA15 mouse model of deafness

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NIAID Data Ecosystem2026-05-02 收录
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DNA editing in the organ of Corti of Pou4f3WT/Q113* mice treated with dual AAV SchABE8e-sgRNA3 after one week. cDNA sequencing to detect editing in Pou4f3WT/Q113* mouse cochlear. Off-target activity analysis of the nine candidate sites identified by Benchling in the organ of Corti of Pou4f3WT/Q113* treated mice treated after one week.

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2024-12-06
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