Copper(II)-Catalyzed Alkoxyhalogenation of Alkynyl Ureas and Amides as a Route to Haloalkylidene-Substituted Heterocycles
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下载链接：
https://figshare.com/articles/dataset/Copper_II_Catalyzed_Alkoxyhalogenation_of_Alkynyl_Ureas_and_Amides_as_a_Route_to_Haloalkylidene_Substituted_Heterocycles/2148913
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资源简介：
A highly effective synthesis of haloalkylidene-substituted
heterocycles
by copper(II)-catalyzed cyclization of alkynyl ureas and secondary
amides has been developed. The reaction, which involves a catalytic
amount of CuCl2 and a stoichiometric amount of N-halosuccinimide, occurs selectively through an alkoxyhalogenation
process. Alternatively, alkoxychlorination and alkoxybromination reactions
can be performed working solely with stoichiometric CuCl2 and CuBr2, respectively.
创建时间：
2016-02-13
