INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z2074076908
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INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z2074076908 Descriptor: 1-(5-azaspiro[2.5]octan-5-yl)-2-(difluoromethoxy)ethan-1-one, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Authors: Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.26 Å) Cite: Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024
INPP5D PanDDA分析组提交数据集——与Z2074076908结合的SHIP1磷酸酶及C2结构域(C2 domain)的晶体结构。配体描述:1-(5-氮杂螺[2.5]辛烷-5-基)-2-(二氟甲氧基)乙-1-酮、二甲基亚砜(DIMETHYL SULFOXIDE)、磷脂酰肌醇3,4,5-三磷酸5-磷酸酶1。
作者:Bradshaw W.J.、Newman J.A.、von Delft F.、Arrowsmith C.H.、Edwards A.M.、Bountra C.、Gileadi O.
提交日期:2020-10-30
发布日期:2020-11-11
最后修改日期:2026-02-18
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.26埃
引用文献:《SHIP1与SHIP2的C2结构域对肌醇5-磷酸酶活性的调控》,《Structure》,2024年
创建时间:
2020-10-30



