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Convergent and Rapid Assembly of Substituted 2-Pyridones through Formation of <i>N</i>-Alkenyl Alkynylamides Followed by Gold-Catalyzed Cycloisomerization

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NIAID Data Ecosystem2026-03-06 收录
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A new method for the convergent and rapid assembly of substituted 2-pyridones was developed through the formation of N-alkenyl alkynylamides (amide-linked 1,5-enynes) by N-acylation of imines with alkynoyl chlorides and the subsequent cationic Au(I)/PPh3-catalyzed cycloisomerization.

创建时间:
2016-02-27
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