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DNA-hypermethylated human gastric cancer circumvents apoptosis in the absence of TP53 mutation (RNA-Seq)

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237451
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Comprehensive gene expression analysis by RNA-seq was performed in various cell lines after p53-MDM2 inhibitor treatment or knockdown of the target genes for novel cancer therapeutic strategies. Nutlin-3 and RG7388 were used as p-53-MDM2 inhibitor. Knockdown of target genes (MDM2, TP53) and control (shNT: Non Target) were perfomed by pLKO.1 lentivirus system in various cell lines.
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2025-08-13
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