LCVD: Low-cost cell-extract viral diagnostics

The datasets contain measurements performed using a configurable colorimetric readout set-up for automated readout from lateral flow test strips.The readout set-up consists of a 3D-printed enclosure device with detector module electronics contained inside, along with a mechanism into which a lateral flow test strip can be inserted. The set-up can be adjusted in x, y and z directions to allow for accurate positioning, alignment and optimization of measurements performed on both model and real lateral flow test strips. Lateral flow test strips can be analysed both without a cartridge housing or within a cartridge housing. The dataset contains the raw measurements and results of the data obtained from the generic test set-up for various configurations of test set-up and the lateral flow test strips analysed. This dataset encompasses various datasets and results obtained during my PhD entitled: Wireless colorimetric readout for resource-limited point-of-care.The work details a hybrid printed and packaged low-cost wireless color detector device. By combining the growing fields of paper-based diagnostics and printed electronics with Southern African clinic perspectives, a scalable, low cost, paper-based solution for result readout and communication was developed.Printed radio frequency identification devices with sensing capabilities were manufactured onto different low-cost and paper-based substrates to assess the practicalfunctionality of these devices. Extensive images and results pertaining to this are included in this dataset.This work was further extended to target colour detection from lateral flow test strip devices and other typical paper-based rapid test formats. The results were comparedto those obtained from manual readout using colour charts, a commercial lateral flow test strip reader and image analysis using ImageJ.本数据集包含通过可配置比色读取装置（configurable colorimetric readout set-up）获取的测量数据，用于侧向流检测试纸条（lateral flow test strips）的自动化读取。该读取装置由内部集成检测模块电子元件的3D打印外壳，以及可插入侧向流检测试纸条的夹持机构组成，可沿x、y、z轴方向调节，以实现对模型与真实侧向流检测试纸条的精准定位、校准与测量优化。侧向流检测试纸条可在无试剂盒外壳或带试剂盒外壳的两种状态下完成分析检测。本数据集包含针对不同配置的测试装置与待分析侧向流检测试纸条，通过通用测试装置获取的原始测量数据与分析结果。本数据集涵盖了本人博士学位论文《面向资源受限场景的即时检测无线比色读取技术》（Wireless colorimetric readout for resource-limited point-of-care）中所获得的各类数据集与分析结果。该项研究详细阐述了一款混合印刷封装式低成本无线比色检测装置：结合蓬勃发展的纸基诊断与印刷电子技术，并立足南非临床场景需求，开发出一套可规模化、低成本的纸基检测结果读取与传输方案。研究将带有传感功能的印刷射频识别（radio frequency identification, RFID）装置制备于各类低成本纸基基底之上，以验证该类装置的实际性能，本数据集包含与此相关的大量图像与分析结果。该项研究后续进一步拓展至侧向流检测试纸条装置与其他典型纸基快速检测格式的颜色检测方向，并将所得结果与三种方式的输出进行对比：基于色卡的人工读取结果、商用侧向流检测试纸条读取仪结果，以及通过ImageJ进行图像分析所得的结果。