Characteristics of participants of cases, noncases and subcohort.

Values presented are mean ± standard deviation or percentage (%) as indicated.1p-values for the difference between cases and noncases, tested by Student t-test (for continuous variables) or Cochran-Armitage trend test (categorical variables).所呈现的数值为均值±标准差或百分比（%），具体标注形式依变量类型而定。注1：病例组与非病例组组间差异的p值，连续变量采用学生t检验（Student t-test），分类变量采用Cochran-Armitage趋势检验（Cochran-Armitage trend test）。