Quantification of pathology marker intensity in immunohistochemistry of Gba mutant mouse brains

The data is quantification of staining area of Gfap, Iba1, and TH in striatal brain sections (Gfap and Iba1) and substantia nigral sections (TH) of mice with five different Gba genotypes (wildtype, L444P/L444P L444P/null, D409H/D409H, D409h/null).本数据集为五种不同Gba基因型小鼠的脑组织染色区域面积定量数据，具体检测方案如下：对纹状体脑组织切片的胶质纤维酸性蛋白（Glial Fibrillary Acidic Protein, Gfap）与离子钙接头蛋白分子1（Ionized Calcium-binding Adapter Molecule 1, Iba1），以及黑质脑组织切片的酪氨酸羟化酶（Tyrosine Hydroxylase, TH）的染色面积进行定量分析；所涉及的小鼠Gba基因型包括野生型、L444P/L444P、L444P/null、D409H/D409H及D409h/null。