遇见数据集

Associated data for The impact of storage conditions on the stability of clinical and experimental pharmaceuticals

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Figshare2021-04-30 更新2026-04-28 收录
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This dataset contains 3 sets of data from the research project "The Impact of Storage Conditions on the Stability of Clinical and Experimental Pharmaceuticals": 1. Raw concentration and pH results for remifentanil and propofol mixed with a number of diluents, both in isolation and when combined. Data was obtained using high performance liquid chromatography (HPLC) and a pH meter. 2. Raw concentration, pH, protein monomer, single-chain protein and bioactivity data for tenecteplase subjected to heat treatment, as well as raw temperature data for a preliminary study determining maximum temperature reached within ambulances (where tenecteplase is often stored). Data was obtained using a thermometer, pH meter, UV spectrometer, size exclusion chromatography (SEC) and a coagulation analyser. 3. Raw concentration and pH data for EBC-46 when subjected to temperature, light, air and pH treatments, as well as its metabolism in an ex vivo model. Data was obtained using high performance liquid chromatography (HPLC), liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS), and a pH meter.

本数据集源自研究项目《储存条件对临床与实验用药物稳定性的影响》,包含三组实验数据: 1. 瑞芬太尼与丙泊酚单独使用或联合使用时,与多种稀释剂混合后的原始浓度及pH值结果。相关检测通过高效液相色谱法(high performance liquid chromatography,HPLC)与pH计完成。 2. 经热处理的替奈普酶的原始浓度、pH值、蛋白质单体、单链蛋白与生物活性数据,以及一项初步研究的原始温度数据——该研究旨在确定替奈普酶常用储存场所急救车内的最高可达温度。检测手段涵盖温度计、pH计、紫外分光光度计、尺寸排阻色谱法(size exclusion chromatography,SEC)与凝血分析仪。 3. 经温度、光照、空气与pH处理后的EBC-46的原始浓度及pH数据,及其在离体模型中的代谢情况。检测手段包括高效液相色谱法(HPLC)、液相色谱-串联质谱联用法(liquid chromatography coupled with tandem mass spectrometry,LC-MS/MS)与pH计。

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2021-04-30
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