Iterative, multimodal, and scalable single-cell profiling for discovery and characterization of signaling regulators

Pilot.rds - A Seurat object containing RNA, Protein (ADT), OligoHash (HTO), Guides (GDO), and Gene-level guides (GDO3) for the pilot experiment in the paper Glossary.rds - A Seurat object containing RNA, Protein (ADT), OligoHash (HTO), Guides (GDO) for the glossary experiment in the paper Validation.rds - A Seurat object containing RNA, Protein (ADT), OligoHash (HTO), Guides (GDO) for the validation experiment in the paper Test.rds - A Seurat object, containing RNA, Protein (ADT), and OligoHash (HTO) to test modeling paradigms on GWPS_mTOR.rds A Seurat object derived from a subset of perturbations in GWPS (Replogle, et al, 2022) with stored pRPS6 model values GWPS_Gloss.rds A Seurat object derived from a subset of perturbations in GWPS (Replogle, et al, 2022) with stored pRPS6 model values GWPS_metadata.csv A csv that has the stored prediction values from GWPS for many many of the tests in the paper