Summary of the results from two replicate direct feeding assays (DFA) for each VS1 compound using Anopheles stephensi that fed on Plasmodium berghei ANKA 2.34 -infected mice pre- and post-injection with either PBS (carrier-only control), PVP
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For each treatment group, the data are summarized into four columns. In the first two columns, the means of the median number of oocysts per mosquito for 4–5 mice per group are given for pre- and post-injection feedings, respectively, with the standard error for each reported in parentheses below the mean. In the third column, the means of percent Inhibition, calculated as the average of (medianpre – medianpost)/medianpre for each mouse, are reported for each treatment group along with standard errors in parentheses. In the fourth column, P-value results of Mann-Whitney U tests are reported for each set of pre- and post-injection feedings. Only P-values that are significant at a Bonferroni-corrected alpha of 0.0028 are given. NS, non-significant.
针对每个处理组,数据均汇总为四列。前两列分别给出了每组4~5只小鼠在注射前喂食与注射后喂食条件下,每只蚊子卵囊数中位数的均值,各均值对应的标准误标注于其下方的括号内。第三列给出各处理组的抑制率均值,该抑制率通过计算每只小鼠的(注射前中位数 - 注射后中位数)/注射前中位数的平均值得到,对应标准误标注于括号中。第四列则给出了针对每组注射前、后喂食数据的曼-惠特尼U检验(Mann-Whitney U tests)的P值结果,仅列出经邦费罗尼校正显著性水平α为0.0028时具有统计学显著性的P值,其中NS代表无统计学显著性(non-significant)。



