Collection of data from literature on proven regulatory links in the ULK1-AMPK-mTORC1 regulatory network.
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Arrows indicate activation, while blocked end lines indicate inhibition between the members (ULK1, AMPK, mTORC1 and “autophagy”) of the network. “Autophagy” refers to the process by which autophagy actually takes place successfully in the cell. The asterisks refer to direct phosphorylation at a given site on the controlled protein. The numbers in the black boxes show the numbered connections in the regulatory network on Fig 1A [13, 15–17, 21, 28–62]. (XLSX)
箭头表示激活作用,而末端带有阻断线的连线则代表该调控网络中Unc-51样激酶1(ULK1)、腺苷酸活化蛋白激酶(AMPK)、雷帕霉素靶蛋白复合物1(mTORC1)与自噬(autophagy)各组分间的抑制效应。“自噬(autophagy)”指细胞内自噬顺利完成的生物学过程。星号代表靶蛋白特定位点上的直接磷酸化修饰。黑框内的数字对应图1A中调控网络的编号连接关系[13, 15–17, 21, 28–62]。(XLSX)
创建时间:
2024-12-26



