five

Nanog affects establishment of chromatin marks at zebrafish Zygotic Genome Activation

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE143439
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In zebrafish embryos, the maternal transcription factors (TFs)Nanog, Pou5f3 and Sox19b activate the early zygotic gene expression. To evaluate the role of Nanog, we examined the changes in H3K27ac and H3K4me3 chromatin modifications in the MZnanog embryos mutant by maternal and zygotic Nanog. We performed ChIP-seq for H3K27ac and H3K4me3 chromatin modifications in the embryos mutant by Nanog transcription factor (MZnanog). Experiments were performed at dome stage (4.3 hours post-fertilization (hpf).
创建时间:
2023-09-21
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