Data and code from: Parasite-mediated inbreeding depression in wild red deer

Inbreeding depression is the reduction in fitness of inbred individuals relative to their more outbred counterparts. Parasitism also reduces fitness and is a route by which inbreeding depression may operate, yet the complete pathway from inbreeding to parasitism to fitness has almost never been documented in the wild. Using high-quality, individual-level data on fitness in juveniles and adult females, longitudinal infection data for three gastrointestinal helminth parasites, and genomic inbreeding coefficients, we test for parasite-mediated inbreeding depression in a wild ungulate population (red deer, Cervus elaphus). We found evidence for parasite-mediated inbreeding depression via strongyle nematodes in juvenile survival, independent of direct adverse effects of inbreeding on survival and indirect effects of inbreeding on survival via birth weight. Inbreeding also reduced fitness in reproductive adults by reducing overwinter survival. Our study reveals three independent pathways by w..., , , Associated data files for:

# Parasite-mediated inbreeding depression in wild red deer

Adam Z. Hasik^1^ (ORCiD ID 0000-0002-4069-7186), Anna M. Hewett^1,2^ (ORCiD 0000-0002-9335-5649),
Katie Maris^1^, Sean J. Morris^1^, Ali Morris^1^, Gregory F. Albery^3^ (ORCiD ID 0000-0001-6260-2662),
Josephine M. Pemberton^1^ (ORCiD ID 0000-0002-0075-1504)

^1^ Institute of Ecology and Evolution, University of Edinburgh, Edinburgh, UK
^2^ Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland
^3^ Department of Zoology, Trinity College Dublin, Dublin, Ireland

*Author for correspondence: Adam Z. Hasik, Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK; email: [[e-mail]](mailto:[e-mail])

This file contains:

Descriptions of the data set associated with the analyses presented in the paper.

inbreeding_code.r – R file containing all code necessary to analyze the data

strong_df.csv, fluke_df.csv, and ecg_df.csv – these are the ...,

近交衰退（Inbreeding depression）指近交个体相对于远交程度更高的同类个体的适合度下降。寄生作用同样会降低个体适合度，同时也是近交衰退可能发挥作用的途径之一，但从近交、寄生到适合度变化的完整通路，在野生种群中几乎从未被证实。本研究依托高质量的幼体与成年雌性个体适合度数据、三种胃肠道寄生蠕虫的纵向感染数据，以及基因组近交系数，对野生有蹄类种群（马鹿，Cervus elaphus）中寄生虫介导的近交衰退进行检验。研究发现，圆线目线虫（strongyle nematodes）介导的近交衰退会影响幼体存活率，该效应独立于近交对存活的直接负面影响，以及近交通过出生体重对存活产生的间接影响。近交还会通过降低越冬存活率，降低繁殖成年个体的适合度。本研究揭示了三条独立的通路，通过……

关联数据集对应：
# 野生马鹿中寄生虫介导的近交衰退

亚当·Z·哈西克（Adam Z. Hasik）^1^（ORCiD编号：0000-0002-4069-7186）、安娜·M·休伊特（Anna M. Hewett）^1,2^（ORCiD编号：0000-0002-9335-5649）、凯蒂·马里斯（Katie Maris）^1^、肖恩·J·莫里斯（Sean J. Morris）^1^、阿里·莫里斯（Ali Morris）^1^、格雷戈里·F·阿尔伯里（Gregory F. Albery）^3^（ORCiD编号：0000-0001-6260-2662）、约瑟芬·M·彭伯顿（Josephine M. Pemberton）^1^（ORCiD编号：0000-0002-0075-1504）

^1^ 英国爱丁堡大学生态与进化研究所，爱丁堡
^2^ 瑞士洛桑大学生态与进化系，洛桑
^3^ 爱尔兰都柏林圣三一学院动物学系，都柏林

通讯作者：亚当·Z·哈西克，英国爱丁堡大学生态与进化研究所，爱丁堡；电子邮箱：[e-mail]

本文件包含：与本文分析相关的数据集说明。

inbreeding_code.r：用于完成本研究数据分析的全部R代码文件
strong_df.csv、fluke_df.csv与ecg_df.csv：为[原文未详述的数据集文件]