Additional file 2 of Pain can’t be carved at the joints: defining function-based pain profiles and their relevance to chronic disease management in healthcare delivery design

Additional File 2: Supplementary Table 1. Overview of number of participants available for each level of analysis. Supplementary Table 2. Excluded Data Fields. Supplementary Table 3A. UKB Pain Variable Description. Supplementary Table 3B. Pain variable loading, sorted by magnitude and organized by pain profile. Supplementary Table 4. Examples of Recoding to standardize data directionality and scale. Supplementary Table 5A. Schaefer-Yeo Anatomical Labels for 7 and 17-Network Schemes. Supplementary Table 5B. Brain Variable loadings for each pain profile. For each profile, we present magnitudes of brain variable loading, sorted in descending value. Supplementary Table 6. Sex, BMI, and Age are significantly associated with all pain profiles in variable ways. Supplementary Table 7. ATC Categories for all medications included in the UKB. Supplementary Table 8. Coding scheme to translate from the UKB to the IASP nomenclature. Supplementary Table 9. Large-scale association studies reveal strong associations of all pain profiles with medications, diagnoses, and phenotypes from multiple disease categories. Supplementary Table 10. Demographic Information for the large, ~ 500,000 participant cohort and for the 34,337 participant cohort, as used to define the pain profiles.