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Relationship between CISH promoter polymorphism and pediatric tuberculosis (TB), stratified by location and severity of the disease.

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Figshare2015-12-02 更新2026-04-29 收录
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1: AA+ AT for rs414171, CC+GC for rs809451; 2: TT for rs414171, GG for rs809451.ORs were adjusted for sex, age, in a logistic regression model.3: OR and P value was calculated between patients and controls, 4: OR and P value was calculated between subgroups of TB (PTB vs EPTB, non SevTB vs SevTB).

1. 针对单核苷酸多态性位点rs414171,基因型组合为AA+AT;针对rs809451位点,基因型组合为CC+GC;2. 针对rs414171位点基因型为TT、rs809451位点基因型为GG的研究对象,采用logistic回归模型(logistic regression model)对比值比(Odds Ratio, OR)进行性别与年龄校正;3. 计算病例组与对照组间的比值比及P值;4. 计算结核病(Tuberculosis, TB)亚组间(肺结核(Pulmonary Tuberculosis, PTB)vs 肺外结核(Extrapulmonary Tuberculosis, EPTB)、非重症结核病(non SevTB)vs 重症结核病(SevTB))的比值比及P值。

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2015-12-02
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