Multivariate Analysis of Biomarker Association with Day 3 SOFA Score.

SOFA = sequential organ failure assessment, β = Beta coefficient for increase in SOFA score with each doubling of biomarker concentration; CI = confidence interval.a Linear regression adjusted for age, gender, presence of infection, admitting service (medical vs. surgical), source of admission (outside hospital vs. emergency room), body mass index, smoking status, diabetes mellitus, chronic renal insufficiency, and cirrhosisb Adjusted for Log2(IL-6) concentration and covariates in a.c Adjusted for Log2(sTNFR-1) concentration and covariates in a.e For the number of tests in this table, a Bonferroni p-3Multivariate Analysis of Biomarker Association with Day 3 SOFA Score.SOFA：即序贯器官衰竭评分（sequential organ failure assessment）；β为生物标志物浓度每翻倍时SOFA评分升高的Beta系数；CI为置信区间（confidence interval）。a 本分析为校正了年龄、性别、感染状态、收治科室（内科 vs. 外科）、入院来源（院外 vs. 急诊室）、体重指数、吸烟状况、糖尿病、慢性肾功能不全及肝硬化的线性回归分析。b 本次校正针对Log₂(白细胞介素6（Interleukin-6，IL-6）)浓度及a项中的协变量进行。c 本次校正针对Log₂(可溶性肿瘤坏死因子受体1（soluble Tumor Necrosis Factor Receptor 1，sTNFR-1）)浓度及a项中的协变量进行。e 针对本表格中的检验次数，采用Bonferroni校正的P值（原文此处存在截断）。生物标志物与第3天SOFA评分的多变量分析。